Vitamin B12 Injection

• Do not use if you:

  • Are allergic to hydroxocobalamin or any other components of the injection.
  • Have an existing medical condition such as Leber’s disease (a hereditary eye condition), as hydroxocobalamin may worsen optic nerve damage.

• Consult a healthcare provider before use if you:

  • Have heart disease, as B12 injections may affect potassium levels.
  • Are pregnant or breastfeeding, though hydroxocobalamin is generally considered safe, it’s best to confirm with your doctor.

• Injection site reactions:
  You may experience temporary redness, swelling, or pain at the injection site. This is usually mild and should subside quickly.

• Discontinue use and seek medical advice if: You experience signs of an allergic reaction, such as difficulty breathing, swelling of the face or throat, or a rash. These reactions are rare but require immediate attention.

• How to administer:

  • Hydroxocobalamin is administered as an intramuscular injection, usually into the buttock or upper arm. It must be given by a healthcare professional.
  • You may need multiple injections to correct a deficiency initially, followed by maintenance doses to prevent relapse.

• Frequency:

  • Initial treatment: 1mg injection every other day for 1-2 weeks, depending on the severity of the deficiency.
  • Maintenance: After the initial course, you may receive 1mg injection every 2-3 months for long-term maintenance.

• Follow-up care:

  • Regular blood tests may be necessary to monitor your B12 levels and adjust your dosage accordingly.
  • Notify your healthcare provider if your symptoms persist or worsen after treatment.

• Storage:

  • Store Hydroxocobalamin vials in a cool, dry place away from direct sunlight. Do not freeze the medication.
  • Ensure that the vials are only handled by a healthcare professional.

Active Ingredient:

• Hydroxocobalamin (1mg/ml): A synthetic form of Vitamin B12 used to treat and prevent B12 deficiency.

Other Ingredients:

• Sodium Chloride (for isotonicity)
• Acetic acid and sodium acetate (for pH adjustment)
• Water for injections

These ingredients help deliver the active compound effectively and ensure the stability of the injection.

Common Side Effects:

1. Mild injection site reactions: Redness, swelling, or pain at the injection site, which should subside within a few hours or days.
2. Headache: Some individuals may experience mild headaches after the injection.
3. Dizziness: Dizziness or lightheadedness may occur, particularly if you have been deficient for a long time.

Less Common Side Effects:

1. Nausea: Some users report mild nausea after receiving the injection.
2. Diarrhea: Gastrointestinal discomfort, including diarrhea, may occur temporarily.

Rare Side Effects:

1. Allergic reactions: Rare but serious allergic reactions may include difficulty breathing, swelling, or a rash. Seek immediate medical attention if these symptoms occur.
2. Low potassium levels: Prolonged use of hydroxocobalamin can cause low potassium levels in some patients, which may result in muscle cramps, weakness, or irregular heartbeat.

• What is Hydroxocobalamin used for?
  Hydroxocobalamin is used to treat and prevent Vitamin B12 deficiency. It is particularly effective for individuals who cannot absorb B12 from food, such as those with pernicious anemia, gastrointestinal issues, or a vegan/vegetarian diet low in B12.

• How often do I need Hydroxocobalamin injections?
  The typical treatment schedule may vary depending on your condition:

  • Initial treatment: 1mg administered intramuscularly every other day for 1-2 weeks.
  • Maintenance: 1mg every 2-3 months as needed to maintain healthy B12 levels. Your doctor will decide on the best schedule based on your condition and response to treatment.

• What are the signs of B12 deficiency?
  Symptoms of B12 deficiency can include:

  • Fatigue or weakness
  • Pale or yellowish skin
  • Nerve problems such as tingling or numbness
  • Cognitive issues such as memory problems or difficulty concentrating
  • Anemia If you suspect a B12 deficiency, it’s important to consult a healthcare provider for testing.

• How is Hydroxocobalamin different from Cyanocobalamin?
  Hydroxocobalamin is a longer-acting form of B12 compared to cyanocobalamin, meaning it stays in the body for a longer period and may require fewer injections.

• Can I take oral supplements instead of injections?
  For people with conditions like pernicious anemia or absorption issues, oral B12 supplements may not be effective. In these cases, injections are the preferred method of treatment as they bypass the digestive system and provide direct absorption.